Clinical Predictors of Weight Gain in Early Breast Cancer Survivors
Abstract
Abstract
Aim: To identify risk factors for weight gain after two years of a breast cancer diagnosis.
Background: Obesity in survivors of early-stage breast cancer has been associated with high disease recurrence rates and lower overall survival rates. Continuous weight gain is an indisputable phenomenon. Identifying factors at the early diagnosis and treatment phase that are associated with weight gain at 2 years later may help to develop further intervention for prevention obesity in breast cancer survivors.
方法:一項回顧性研究旨在審查臺灣癌症中心1901年早期乳腺癌倖存者的病歷。提取的數據包括人口統計學、過去病史、癌症治療、腫瘤特徵、診斷時體重指數和24個月體重。
結果:樣本的平均年齡為50.3歲(+10.7)其中大部分是絕經前,第二階段和BMI範圍從18.5到24公斤/平方米診斷。他們中的大多數接受乳房切除術(65.9%),化療(68.8%),放射治療(64.6%)和激素治療 (63%).手術后24個月,乳腺癌患者平均體重增加了0.4公斤:但其中21.6%的人獲得了5%或更多。乳腺癌倖存者那些在診斷時絕經前,不到高中教育,接受亞得里亞黴素劑,環磷醯胺劑,並在手術后增加5%或以上的體重有顯著更高的風險,增加5%或更多在診斷后2年。
結論:我們的研究結果表明,絕經前婦女或接受較少正規教育的婦女,在乳腺癌治療后體重增加的風險較高。有必要為這些高風險群體參與健康的體重管理
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